Possible side effects of Aspirin

All drugs have side effects, and Aspirin is no exception. However, Aspirin is a commonly used medicine, and doesn’t normally cause serious problems. The doses used in PROVENT are very low, and most people won’t notice any side effects at all. If you haven’t previously experienced side effects taking Aspirin, you probably won’t experience any taking it as part of PROVENT. If you have had an unpleasant reaction to Aspirin before, please let your study doctor/nurse know, before commencing the study.

The main concern with Aspirin is that it can irritate the lining of the stomach and cause bleeding in some people. This is unlikely to happen with such a small dose, but if you unexpectedly develop severe indigestion or stomach pain it would be best to stop taking your tablets until you’ve spoken to your study doctor/nurse.

Early on in the trial you’ll be tested for the bacteria, Helicobacter pylori, known to cause gastric bleeding in some people. We’d rather not put you on Aspirin long-term if you have these bacteria in your gut, as it may slightly increase the risk of bleeding. If your test is positive, you will be treated with antibiotics while you continue to take your PROVENT drugs. In general practice doctors will usually prescribe Aspirin without checking for Helicobacter pylori first, so this is simply an extra precaution.

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